Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571866 | 0.84 | SPHK1 (0.46) | PPARGHTR2CDRD2DRD3PRMT5 | |
| SCHEMBL2912686 | 0.80 | HTR2C (0.64) | HTR2CDRD2PDE4APDE4BPDE4C | |
| SCHEMBL14830660 | 0.79 | MGLL (0.44) | HTR2CESR2 | |
| SCHEMBL4359622 | 0.75 | CYP3A4 (0.49) | PPARGHTR2CESR2PDE4APDE4B | |
| SCHEMBL730107 | 0.74 | ESR2 (0.47) | HTR2CESR2PDE4APDE4BPDE4C | |
| SCHEMBL25049286 | 0.74 | PDE4A (0.43) | PPARGHTR2CESR2PDE4APDE4B | |
| SCHEMBL7005161 | 0.73 | PPARG (0.50) | PPARGHRH3PDE4APDE4BPDE4C | |
| SCHEMBL24461308 | 0.73 | GRIN1 (0.50) | — | |
| SCHEMBL15492773 | 0.73 | PPARG (0.50) | PPARGHRH3PDE4APDE4BPDE4C | |
| SCHEMBL7057736 | 0.71 | ADRA1A (0.56) | HTR2CDRD2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881221-B1 | DIOXANE DERIVATIVES, LIQUID-CRYSTAL COMPOSITIONS CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY DEVICES MADE BY USING THE SAME | JNC CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-6235355-B1 | OPTICAL APPARATUS WITH LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0881221-A1 | DIOXANE DERIVATIVES, LIQUID-CRYSTAL COMPOSITIONS CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY DEVICES MADE BY USING THE SAME | CHISSO CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |