Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859537 | 0.89 | PTGS1 (0.56) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL10334608 | 0.83 | PTGS1 (0.76) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL30842776 | 0.79 | PTGS1 (0.70) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL29377983 | 0.78 | ADORA3 (0.69) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL29377471 | 0.78 | ADORA3 (0.69) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL26326 | 0.77 | PTGS1 (1.00) | ADORA3MIFPTGS1PDE4APDE4D | |
| Potassium SCHEMBL29375000 | 0.77 | ADORA3 (0.68) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL29366981 | 0.77 | PTGS1 (1.00) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL5455197 | 0.76 | PTGS1 (0.98) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL10415468 | 0.76 | ADORA3 (0.78) | ADORA3MIFPTGS1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695547-B1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO LTD (JP) | 2001-08-08 | — | — | EP | claimed |
| US-6166068-A | Immunomodulator, cell adhesion inhibitor, and agent for treating, and preventing autoimmune diseases | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | claimed |
| US-5922755-A | ADMINSTERING 4H-1-BENZOPYRAN-4-ONE DERIVATIVE | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | claimed |
| EP-0695547-A1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-02-07 | — | — | EP | claimed |
| EP-0695547-B1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO LTD (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-6166068-A | Immunomodulator, cell adhesion inhibitor, and agent for treating, and preventing autoimmune diseases | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| US-5922755-A | ADMINSTERING 4H-1-BENZOPYRAN-4-ONE DERIVATIVE | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0695547-A1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-02-07 | — | — | EP | disclosed |