Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859528 | 0.89 | ADORA3 (0.63) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL7859555 | 0.81 | PTGS2 (0.48) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10334608 | 0.78 | PTGS1 (0.76) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL30842776 | 0.74 | PTGS1 (0.70) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL29377983 | 0.73 | ADORA3 (0.69) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL29377471 | 0.73 | ADORA3 (0.69) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10415468 | 0.73 | ADORA3 (0.78) | PTGS1ADORA3MIFPDE4APDE4D | |
| Iguratimod SCHEMBL26326 | 0.72 | PTGS1 (1.00) | PTGS1ADORA3MIFPDE4APDE4D | |
| Iguratimod SCHEMBL29366981 | 0.72 | PTGS1 (1.00) | PTGS1ADORA3MIFPDE4APDE4D | |
| Potassium SCHEMBL29375000 | 0.72 | ADORA3 (0.68) | PTGS1ADORA3MIFPDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695547-B1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO LTD (JP) | 2001-08-08 | — | — | EP | claimed |
| US-6166068-A | Immunomodulator, cell adhesion inhibitor, and agent for treating, and preventing autoimmune diseases | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | claimed |
| US-5922755-A | ADMINSTERING 4H-1-BENZOPYRAN-4-ONE DERIVATIVE | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | claimed |
| EP-0695547-A1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-02-07 | — | — | EP | claimed |
| EP-0695547-B1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO LTD (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-6166068-A | Immunomodulator, cell adhesion inhibitor, and agent for treating, and preventing autoimmune diseases | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| US-5922755-A | ADMINSTERING 4H-1-BENZOPYRAN-4-ONE DERIVATIVE | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0695547-A1 | IMMUNOMODULATOR, CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-02-07 | — | — | EP | disclosed |