Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859886 | 0.86 | NR1H2 (0.46) | ABCB1NR1H2NR1H3PARP1DPP4 | |
| SCHEMBL7859737 | 0.83 | MCL1 (0.35) | ABCB1MCL1PRMT5BACE1BACE2 | |
| SCHEMBL7859855 | 0.81 | ABCB1 (0.38) | ABCB1NR1H2NR1H3DPP4SRC | |
| SCHEMBL7862618 | 0.80 | GPR119 (0.42) | ABCB1NR1H2NR1H3PARP1 | |
| SCHEMBL7853709 | 0.80 | ABCB1 (0.40) | ABCB1NR1H2NR1H3PARP1DPP4 | |
| SCHEMBL4292542 | 0.79 | ABCB1 (0.47) | ABCB1MCL1PRMT5NR1H2NR1H3 | |
| SCHEMBL30207112 | 0.79 | ABCB1 (0.47) | ABCB1MCL1PRMT5NR1H2NR1H3 | |
| SCHEMBL19708616 | 0.78 | ABCB1 (0.56) | ABCB1MCL1NR1H2NR1H3PARP1 | |
| SCHEMBL7860716 | 0.77 | ABCB1 (0.40) | ABCB1PRMT5NR1H2NR1H3PARP1 | |
| SCHEMBL1464254 | 0.76 | SRC (0.47) | ABCB1PARP1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |