Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859886 | 0.87 | NR1H2 (0.46) | ABCB1NR1H2NR1H3DPP4MEN1 | |
| SCHEMBL7860565 | 0.82 | ABCB1 (0.39) | ABCB1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL7859855 | 0.82 | ABCB1 (0.38) | ABCB1NR1H2NR1H3DPP4MEN1 | |
| SCHEMBL7859559 | 0.82 | ABCB1 (0.35) | ABCB1NR1H2NR1H3SIRT2MAPT | |
| SCHEMBL7859533 | 0.80 | ABCB1 (0.40) | ABCB1NR1H2NR1H3DPP4PARP1 | |
| SCHEMBL30207112 | 0.80 | ABCB1 (0.47) | ABCB1NR1H2NR1H3PARP1SRC | |
| SCHEMBL4292542 | 0.80 | ABCB1 (0.47) | ABCB1NR1H2NR1H3PARP1SRC | |
| SCHEMBL7862618 | 0.79 | GPR119 (0.42) | ABCB1NR1H2NR1H3PARP1 | |
| SCHEMBL30538732 | 0.78 | NR1H2 (0.35) | ABCB1NR1H2MEN1KMT2APARP1 | |
| SCHEMBL7852970 | 0.78 | ACHE (0.40) | ABCB1NR1H2NR1H3DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |