Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12574909 | 0.87 | ABL1 (0.43) | POLBHSD17B10KMT2AALDH1A1HPGD | |
| SCHEMBL8706781 | 0.86 | POLB (0.42) | POLBTERTMAPTKMT2ANPSR1 | |
| SCHEMBL12574913 | 0.78 | ABL1 (0.45) | POLBMAPTHSD17B10KMT2ATSHR | |
| SCHEMBL16572051 | 0.76 | GAA (0.41) | MAPTHSD17B10ALDH1A1EGFRERBB2 | |
| SCHEMBL11502422 | 0.76 | GAA (0.43) | MAPTHSD17B10MEN1KMT2ANPSR1 | |
| SCHEMBL15517362 | 0.73 | HSD17B10 (0.50) | POLBMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL1032834 | 0.72 | ESR1 (0.46) | HSD17B10MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18323995 | 0.71 | LMNA (0.42) | MAPTHSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL1275788 | 0.71 | HSPA5 (0.44) | POLBMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL7860247 | 0.71 | VCAM1 (0.43) | NPSR1TSHRALDH1A1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855998-B1 | ANTIOXIDANTS CONTAINING PHENOL GROUPS AND AROMATIC AMINE GROUPS | CIBA SC HOLDING AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0855998-A1 | ANTIOXIDANTS CONTAINING PHENOL GROUPS AND AROMATIC AMINE GROUPS | Ciba Specialty Chemicals Holding Inc. (CH) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997014678-A1 | ANTIOXIDANTS CONTAINING PHENOL GROUPS AND AROMATIC AMINE GROUPS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-04-24 | — | — | WO | disclosed |