SCHEMBL7860403

SCHEMBL7860403

C=Cc1c(C=Cc2ccccc2C)cccc1C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 4/20 0.41
CFTR P13569 1/20 0.41
HSD17B10 Q99714 1/20 0.41
BACE1 P56817 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
NR4A2 P43354 1/20 0.40
KDM4E B2RXH2 5/20 0.40
POLB P06746 4/20 0.40
ATM Q13315 1/20 0.40
MYC P01106 1/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
ALOX12 P18054 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869865 0.84 NR4A2 (0.46) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL5047779 0.84 LMNA (0.46) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL16955450 0.81 LMNA (0.43) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL7860407 0.81 MYC (0.47) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL22481046 0.80 TSHR (0.52) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL17146037 0.75 CA1 (0.43) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL61520 0.75 TSHR (0.55) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL69553 0.75 BACE1 (0.60) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL69552 0.75 BACE1 (0.60) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL16958924 0.74 ALDH1A1 (0.48) LMNATSHRALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6312885-B1 WITH IMAGE FORMING LAYERS OF DIFFERENT THERMAL EXPANSION COEFFICIENTS FUJI PHOTO FILM CO., LTD. (JP) 2001-11-06 US disclosed