Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856790 | 0.86 | PARP1 (0.34) | PARP1UCHL1MEN1KMT2AABCB1 | |
| SCHEMBL7859048 | 0.84 | HTRA1 (0.38) | PARP1UCHL1ABCB1HTRA1PRMT5 | |
| SCHEMBL6404153 | 0.84 | HTRA1 (0.38) | PARP1UCHL1ABCB1HTRA1PRMT5 | |
| SCHEMBL7852853 | 0.84 | ABCB1 (0.36) | PARP1UCHL1MEN1KMT2AABCB1 | |
| SCHEMBL9096789 | 0.84 | PARP1 (0.35) | PARP1UCHL1MEN1KMT2A | |
| SCHEMBL7860701 | 0.83 | MEN1 (0.36) | PARP1UCHL1MEN1KMT2AABCB1 | |
| SCHEMBL7859900 | 0.81 | GPR119 (0.33) | PARP1ABCB1NR1H2NR1H3GPR119 | |
| SCHEMBL7853700 | 0.79 | VHL (0.38) | PARP1KMT2ANR1H2NR1H3GPR119 | |
| SCHEMBL7852970 | 0.78 | ACHE (0.40) | PARP1UCHL1MEN1KMT2AABCB1 | |
| SCHEMBL26384453 | 0.78 | PARP1 (0.33) | PARP1UCHL1MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |