Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404153 | 0.88 | HTRA1 (0.38) | UCHL1PARP1HTRA1PRMT5WDR77 | |
| SCHEMBL7859048 | 0.88 | HTRA1 (0.38) | UCHL1PARP1HTRA1PRMT5WDR77 | |
| SCHEMBL7853700 | 0.84 | VHL (0.38) | KMT2APARP1NR1H2NR1H3KCNK3 | |
| SCHEMBL7854724 | 0.83 | ABCB1 (0.34) | MEN1KMT2AMAPTNR1H2NR1H3 | |
| SCHEMBL7860558 | 0.83 | PARP1 (0.37) | MEN1KMT2AUCHL1PARP1HTRA1 | |
| SCHEMBL7859630 | 0.82 | VHL (0.35) | PARP1NR1H2NR1H3PRMT5WDR77 | |
| SCHEMBL7859559 | 0.82 | ABCB1 (0.35) | MEN1KMT2AMAPTNR1H2NR1H3 | |
| SCHEMBL7860702 | 0.79 | NR1H3 (0.36) | NR1H2NR1H3BCL2BCL2L1MCL1 | |
| SCHEMBL7863039 | 0.78 | GPR119 (0.35) | P2RX3MCL1ABCB1 | |
| SCHEMBL7859734 | 0.78 | GPR119 (0.35) | P2RX3MCL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |