Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860654 | 0.92 | KMT2A (0.53) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7785382 | 0.89 | KMT2A (0.63) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6816627 | 0.75 | NPC1 (0.69) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7782465 | 0.73 | MAPT (0.41) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7078679 | 0.72 | FADS1 (0.55) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6814369 | 0.72 | MEN1 (0.60) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7567771 | 0.72 | MEN1 (0.48) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7716934 | 0.71 | RAB9A (0.81) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7911933 | 0.71 | KMT2A (0.62) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7785147 | 0.70 | MEN1 (0.49) | KMT2AMEN1TDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |