Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781804 | 0.87 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL7805543 | 0.87 | TDP1 (0.43) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL9521184 | 0.86 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL10706956 | 0.86 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL9265469 | 0.86 | DPP4 (0.43) | TDP1CCR5ATMRAB9AALDH1A1 | |
| SCHEMBL7805572 | 0.86 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL9519179 | 0.86 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL9138797 | 0.85 | TDP1 (0.42) | TDP1CCR5ATMRAB9ANPC1 | |
| SCHEMBL7811582 | 0.85 | TDP1 (0.43) | TDP1CCR5ATMALDH1A1 | |
| SCHEMBL9569904 | 0.85 | TDP1 (0.43) | TDP1CCR5ATMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |