Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107574 | 0.88 | CCR5 (0.42) | TDP1ATMCCR5 | |
| SCHEMBL8112388 | 0.87 | CCR5 (0.39) | TDP1ATMCCR5RAB9ADPP8 | |
| SCHEMBL9519179 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9A | |
| SCHEMBL7805572 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9AALDH1A1 | |
| SCHEMBL10706956 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9A | |
| SCHEMBL9521184 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9A | |
| SCHEMBL8781804 | 0.85 | TDP1 (0.42) | TDP1ATMCCR5RAB9AALDH1A1 | |
| SCHEMBL9138797 | 0.85 | TDP1 (0.42) | TDP1ATMCCR5RAB9AALDH1A1 | |
| SCHEMBL7860693 | 0.85 | TDP1 (0.43) | TDP1ATMCCR5RAB9AALDH1A1 | |
| SCHEMBL7805543 | 0.85 | TDP1 (0.43) | TDP1ATMCCR5RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521524-A1 | Aminooxypyrrolidinylthiocarbapenem compounds | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-01-07 | — | — | EP | disclosed |