Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519179 | 1.00 | TDP1 (0.42) | TDP1ATMCCR5RAB9ASIRT2 | |
| SCHEMBL10706956 | 1.00 | TDP1 (0.42) | TDP1ATMCCR5RAB9ASIRT2 | |
| SCHEMBL7811582 | 0.89 | TDP1 (0.43) | TDP1ATMCCR5 | |
| SCHEMBL7805572 | 0.87 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL8781804 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL9138797 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL7860693 | 0.86 | TDP1 (0.43) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL7805543 | 0.86 | TDP1 (0.43) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL9569904 | 0.86 | TDP1 (0.43) | TDP1ATMCCR5RAB9A | |
| SCHEMBL9368219 | 0.86 | CCR5 (0.39) | TDP1CCR5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |