Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859856 | 0.91 | KLK7 (0.37) | KLK7ABCB1CREBBPEP300PDE4B | |
| SCHEMBL7859559 | 0.87 | ABCB1 (0.35) | KLK7ABCB1MAPTNPSR1GHSR | |
| SCHEMBL7854724 | 0.85 | ABCB1 (0.34) | ABCB1MAPTNPSR1PDE4B | |
| SCHEMBL7860702 | 0.84 | NR1H3 (0.36) | ABCB1GHSRGPR119 | |
| SCHEMBL6404153 | 0.80 | HTRA1 (0.38) | ABCB1PRMT5GPR119 | |
| SCHEMBL7859048 | 0.80 | HTRA1 (0.38) | ABCB1PRMT5GPR119 | |
| SCHEMBL7860716 | 0.79 | ABCB1 (0.40) | KLK7ABCB1CREBBPEP300PRMT5 | |
| SCHEMBL7852779 | 0.79 | KLK7 (0.33) | KLK7ABCB1ICAM1SELEGPR119 | |
| SCHEMBL7860701 | 0.77 | MEN1 (0.36) | ABCB1MAPTPRMT5 | |
| SCHEMBL9399973 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |