Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 10/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859559 | 0.90 | ABCB1 (0.35) | NR1H3NR1H2GPR119ABCB1MCL1 | |
| SCHEMBL7854724 | 0.88 | ABCB1 (0.34) | NR1H3NR1H2ABCB1MCL1BCL2 | |
| SCHEMBL7860696 | 0.84 | KLK7 (0.37) | GPR119ABCB1GHSR | |
| SCHEMBL6404153 | 0.82 | HTRA1 (0.38) | GPR119ABCB1 | |
| SCHEMBL7859048 | 0.82 | HTRA1 (0.38) | GPR119ABCB1 | |
| SCHEMBL7859900 | 0.81 | GPR119 (0.33) | NR1H3NR1H2GPR119ABCB1MCL1 | |
| SCHEMBL7860701 | 0.79 | MEN1 (0.36) | NR1H3NR1H2ABCB1MCL1BCL2 | |
| SCHEMBL7862618 | 0.77 | GPR119 (0.42) | NR1H3NR1H2GPR119ABCB1 | |
| SCHEMBL7853700 | 0.77 | VHL (0.38) | NR1H3NR1H2GPR119MCL1 | |
| SCHEMBL7859630 | 0.77 | VHL (0.35) | NR1H3NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |