Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | GHSR | Q92847 | 4/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854724 | 0.91 | ABCB1 (0.34) | ABCB1MAPTNPSR1NR1H3NR1H2 | |
| SCHEMBL7860702 | 0.90 | NR1H3 (0.36) | ABCB1NR1H3NR1H2GHSRGPR119 | |
| SCHEMBL7860696 | 0.87 | KLK7 (0.37) | ABCB1MAPTNPSR1GHSRKLK7 | |
| SCHEMBL7859048 | 0.85 | HTRA1 (0.38) | ABCB1GPR119JAK2JAK1 | |
| SCHEMBL6404153 | 0.85 | HTRA1 (0.38) | ABCB1GPR119JAK2JAK1 | |
| SCHEMBL7862941 | 0.85 | ABCB1 (0.32) | ABCB1MAPTNPSR1GPR119SIRT2 | |
| SCHEMBL7853709 | 0.82 | ABCB1 (0.40) | ABCB1MAPTNPSR1NR1H3NR1H2 | |
| SCHEMBL7860701 | 0.82 | MEN1 (0.36) | ABCB1MAPTNR1H3NR1H2MCL1 | |
| SCHEMBL7859630 | 0.80 | VHL (0.35) | NR1H3NR1H2GPR119 | |
| SCHEMBL7853700 | 0.80 | VHL (0.38) | NR1H3NR1H2GPR119MCL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |