Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860796 | 0.83 | KMT2A (0.41) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL8493070 | 0.83 | KMT2A (0.41) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL13499619 | 0.82 | L3MBTL1 (0.46) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL4286531 | 0.79 | OPRM1 (0.44) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL11396848 | 0.79 | NPSR1 (0.41) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL2325685 | 0.78 | NPSR1 (0.44) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL28753474 | 0.76 | MTNR1A (0.45) | KMT2AMEN1NPSR1ALDH1A1MAPT | |
| SCHEMBL9505872 | 0.76 | KMT2A (0.46) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL4131826 | 0.76 | NPSR1 (0.43) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL8392334 | 0.76 | NPSR1 (0.43) | KMT2AMEN1NPSR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149072-A1 | SULFONAMIDE HYDROXAMATES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037436-A1 | SULFONAMIDE HYDROXAMATES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-29 | — | — | WO | disclosed |