SCHEMBL7860922

SCHEMBL7860922

C[Si](C)(C)N(B(Cl)C1c2ccccc2-c2ccccc21)[Si](C)(C)C.[Li]CCCC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6428815 0.85 GPR3 (0.39) ACHESLC22A2SLC22A3GPR3
SCHEMBL6428369 0.63 KMT2A (0.40) ACHESLC22A2SLC22A3GPR3
SCHEMBL27462668 0.60 GPR3 (0.41) BCHEACHESLC22A2SLC22A3GPR3
SCHEMBL4034020 0.60 ACHE (0.47) BCHEACHEGPR3
SCHEMBL313685 0.60 ACHE (0.55) BCHEACHEGPR3
SCHEMBL19547942 0.59 TSHR (0.38)
Toluene SCHEMBL1752732 0.59 TSHR (0.55) ACHE
Naphthalene SCHEMBL11122598 0.59 HTT (0.41)
Naphthalene SCHEMBL11122594 0.59 HTT (0.41)
SCHEMBL877438 0.58 HTR2A (0.56) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141034-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP Chemicals Limited (GB) 2001-10-10 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed