Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859329 | 0.89 | CNR1 (0.56) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL7924583 | 0.85 | CNR1 (0.58) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL7859576 | 0.85 | ADRA1D (0.47) | CNR1NPC1KDM4EALDH1A1MAPT | |
| SCHEMBL7931370 | 0.82 | CNR1 (0.51) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL9336481 | 0.79 | CNR1 (0.62) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL7860372 | 0.78 | PLK1 (0.45) | SMN1; SMN2MEN1KMT2A | |
| Potassium Ion SCHEMBL7853738 | 0.78 | HTR1A (0.41) | CNR2MEN1KMT2A | |
| SCHEMBL8792140 | 0.78 | CNR1 (0.66) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| Potassium Ion SCHEMBL7860570 | 0.78 | MEN1 (0.44) | CNR2MEN1KMT2A | |
| SCHEMBL7853735 | 0.77 | CNR1 (0.70) | CNR1CREBBPPOLBL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753511-B1 | 4-INDOL-1-YL BUTYRIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF ALPHA1-ADRENERGIC RECEPTORS AND TESTOSTERONE 5ALPHA-REDUCTASES | ZERIA PHARM CO LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5760040-A | THERAPEUTIC AGENT FOR PROSTATIC HYPERTROPHY, URINATION DISORDER, ALOPECIA AND ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0753511-A1 | INDOLE DERIVATIVE AND MEDICINE CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |