Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457575 | 0.77 | HSD11B1 (0.48) | HSD11B1IKBKBDYRK2MAPTTP53 | |
| SCHEMBL2000509 | 0.77 | HSD11B1 (0.48) | HSD11B1IKBKBDYRK2MAPTTP53 | |
| SCHEMBL3220923 | 0.76 | HSD11B1 (0.42) | HSD11B1IKBKBDYRK2MAPTTP53 | |
| SCHEMBL5742413 | 0.72 | HSD11B1 (0.36) | HSD11B1POLBBCHE | |
| SCHEMBL7224974 | 0.71 | TSHR (0.50) | MAPTTP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL22440499 | 0.71 | TRPA1 (0.32) | ALDH1A1KMT2ATRPA1MEN1 | |
| SCHEMBL5415180 | 0.71 | NFE2L2 (0.54) | IKBKBDYRK2MAPK1 | |
| SCHEMBL7865931 | 0.71 | TRPA1 (0.55) | DYRK2MAPTTP53CYP1A1CYP1A2 | |
| SCHEMBL3368866 | 0.71 | TRPA1 (0.60) | HSD11B1MAPTTP53POLBCYP1A2 | |
| Acetonitrile SCHEMBL28192655 | 0.71 | KMT2A (0.48) | HSD11B1IKBKBDYRK2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |