Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314167 | 0.75 | HPGD (0.47) | ADORA2AATMMAPK1L3MBTL1TDP1 | |
| SCHEMBL6513070 | 0.69 | MAPK1 (0.56) | ATMMAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL25284100 | 0.65 | TMEM97 (0.47) | MAPK1L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL20505282 | 0.65 | HPGD (0.49) | L3MBTL1ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL20797039 | 0.64 | LMNA (0.40) | L3MBTL1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22864698 | 0.63 | ADORA2A (0.41) | ADORA2AATMMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL2927270 | 0.62 | TMEM97 (0.49) | L3MBTL1ALDH1A1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2924440 | 0.62 | TMEM97 (0.49) | L3MBTL1ALDH1A1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL694128 | 0.62 | ESRRG (0.48) | ADORA2AATMMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL6810401 | 0.61 | ATM (0.63) | ATMMAPK1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |