Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 3/20 | 0.39 |
| ▸ | PPIF | P30405 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861286 | 0.90 | MEN1 (0.42) | MEN1MAPTKMT2APPIAPPIF | |
| SCHEMBL7859925 | 0.84 | HTR1A (0.46) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7859923 | 0.84 | CYP19A1 (0.36) | MAPTCYP19A1CYP11B1CYP11B2CNR1 | |
| SCHEMBL7861067 | 0.81 | KMT2A (0.45) | MEN1MAPTKMT2ACYP19A1CYP11B1 | |
| SCHEMBL7861310 | 0.80 | MAPT (0.44) | MEN1MAPTKMT2ACYP19A1CYP11B1 | |
| SCHEMBL7854338 | 0.76 | HTR1A (0.36) | MAPT | |
| SCHEMBL7860104 | 0.76 | SMN1; SMN2 (0.41) | MEN1MAPTKMT2APOLBALDH1A1 | |
| SCHEMBL7859944 | 0.75 | HTR1A (0.41) | MEN1MAPTKMT2APOLBALDH1A1 | |
| SCHEMBL7861096 | 0.75 | KCNH2 (0.46) | — | |
| SCHEMBL7861401 | 0.75 | ABCB1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |