Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPIF | P30405 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861067 | 0.90 | KMT2A (0.45) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL7861125 | 0.90 | MEN1 (0.39) | MAPTKMT2AMEN1PPIAALDH1A1 | |
| SCHEMBL7861001 | 0.85 | NPC1 (0.35) | CYP19A1CYP11B1CYP11B2ALDH1A1CNR1 | |
| SCHEMBL7864331 | 0.82 | NPC1 (0.40) | MAPTKMT2AMEN1CYP19A1PPIA | |
| SCHEMBL7861144 | 0.80 | MEN1 (0.44) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL7860112 | 0.78 | NISCH (0.31) | MAPTKMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7860116 | 0.77 | EZH2 (0.36) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL7862260 | 0.75 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2ALDH1A1CNR1 | |
| SCHEMBL7861286 | 0.73 | MEN1 (0.42) | MAPTKMT2AMEN1PPIAALDH1A1 | |
| SCHEMBL20917661 | 0.71 | MEN1 (0.58) | MAPTKMT2AMEN1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |