Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858263 | 0.84 | RXRA (0.47) | NOTUMRXRARXRBRXRGDAO | |
| SCHEMBL2299901 | 0.84 | XDH (0.43) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2094822 | 0.81 | MAPT (0.41) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2089711 | 0.81 | NOTUM (0.39) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2091883 | 0.80 | IDO1 (0.41) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5536299 | 0.80 | ADH1B (0.42) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL30486158 | 0.79 | PTPN7 (0.47) | NPSR1EPHX1DAOPTPN7DUSP3 | |
| SCHEMBL250310 | 0.79 | PTPN7 (0.47) | NPSR1EPHX1DAOPTPN7DUSP3 | |
| SCHEMBL1639279 | 0.79 | NOTUM (0.40) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL30626572 | 0.79 | NOTUM (0.40) | MAPTLMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |