Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479582 | 0.83 | IDO1 (0.35) | ALDH1A1CYP3A4 | |
| SCHEMBL444619 | 0.83 | LOXL2 (0.38) | LOXL2HSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL444754 | 0.77 | LOXL2 (0.41) | LOXL2HSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL183664 | 0.77 | LOXL2 (0.41) | LOXL2HSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL145091 | 0.76 | TSHR (0.52) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8456421 | 0.74 | IDO1 (0.50) | HSD17B10ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| Water SCHEMBL28226317 | 0.74 | TSHR (0.50) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| Phosphine SCHEMBL28323888 | 0.74 | TSHR (0.50) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL896480 | 0.74 | ALDH1A1 (0.30) | ALDH1A1CYP3A4 | |
| SCHEMBL28815635 | 0.74 | SNCA (0.39) | LOXL2HSD17B10ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |