Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL3664363 | 0.78 | MEN1 (0.73) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| Naphthalene SCHEMBL28210871 | 0.77 | KDM4E (0.55) | HPGDSMN1; SMN2HSD17B10MEN1KMT2A | |
| Benzenethiol SCHEMBL28334739 | 0.76 | MEN1 (0.48) | SMN1; SMN2MEN1KMT2AKDM4EGAA | |
| Phenol SCHEMBL11797218 | 0.76 | CA12 (0.50) | SMN1; SMN2MEN1KMT2AKDM4EGAA | |
| Aniline SCHEMBL74276 | 0.76 | TSHR (0.50) | SMN1; SMN2HSD17B10MEN1KMT2AKDM4E | |
| Phenol SCHEMBL28582780 | 0.76 | CA12 (0.50) | SMN1; SMN2MEN1KMT2AKDM4EGAA | |
| Toluene SCHEMBL3946837 | 0.76 | LMNA (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Fluoride SCHEMBL28586370 | 0.75 | HPGD (0.92) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Fluoride SCHEMBL28039575 | 0.75 | HPGD (0.92) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Morpholine SCHEMBL11760744 | 0.74 | MEN1 (0.46) | HPGDSMN1; SMN2HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174743-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-06-08 | — | — | US | disclosed |
| EP-4190589-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | The Goodyear Tire & Rubber Company (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4023460-A1 | SULFUR CURABLE RUBBER FORMULATION, TIRE COMPONENT AND SILICA | The Goodyear Tire & Rubber Company (US) | 2022-07-06 | — | — | EP | disclosed |
| US-20220204722-A1 | SILICA REINFORCED RUBBER | GOODYEAR TIRE & RUBBER COMPANY, THE | 2022-06-30 | — | — | US | disclosed |
| US-10087320-B2 | Conductive polymer-matrix compositions and uses thereof | POLYDROP, LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-20180237626-A1 | CONDUCTIVE POLYMER-MATRIX COMPOSITIONS AND USES THEREOF | POLYDROP, LLC | 2018-08-23 | — | — | US | disclosed |
| WO-2018151837-A1 | CONDUCTIVE POLYMER-MATRIX COMPOSITIONS AND USES THEREOF | POLYDROP, LLC (US) | 2018-08-23 | — | — | WO | disclosed |
| US-20180240565-A1 | CONDUCTIVE POLYMER-MATRIX COMPOSITIONS AND USES THEREOF | POLYDROP LLC (US) | 2018-08-23 | — | — | US | disclosed |
| US-9127167-B2 | Functional reinforcing fillers modified with alkenylalkoxysilane and preparing method of the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-09-08 | — | — | US | disclosed |
| US-20140102332-A1 | FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-04-17 | — | — | US | disclosed |
| US-8129458-B2 | Functional reinforcing filler and method of preparing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-03-06 | — | — | US | disclosed |
| US-20110098389-A1 | Functional reinforcing filler and method of Preparing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-28 | — | — | US | disclosed |
| US-7704552-B2 | Process for producing chemically treated amorphous precipitated silica | PPG INDUSTRIES OHIO, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7687107-B2 | Process for producing chemically modified amorphous precipitated silica | PPG INDUSTRIES OHIO, INC. (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1836265-A2 | PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS | PPG Industries Ohio, Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20060225615-A1 | Treated filler and process and producing | PPG INDUSTRIES OHIO, INC. | 2006-10-12 | — | — | US | disclosed |
| WO-2006065578-A2 | PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS | PPG INDUSTRIES OHIO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20050176852-A1 | Process for producing chemically treated fillers | PPG INDUSTRIES OHIO, INC. | 2005-08-11 | — | — | US | disclosed |
| US-20050131107-A1 | Process for producing chemically modified fillers | QEMETICA S.A. (PL) | 2005-06-16 | — | — | US | disclosed |
| US-4002594-A | THIOMORPHOLINE | PPG INDUSTRIES, INC. (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140102332-A1 | FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME | TST, MSN, TELO2 | MAPT 3253/4885HPGD 2293/4885SMN1; SMN2 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.