SCHEMBL7861327

SCHEMBL7861327

CCS(=O)(=O)c1cc(C(N)=O)ccc1C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.41
PARP10 Q53GL7 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
CA2 P00918 1/20 0.39
PARP1 P09874 2/20 0.38
KMT2A Q03164 1/20 0.37
LCK P06239 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
BRD4 O60885 1/20 0.37
BRPF1 P55201 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16990464 0.82 SLC9A1 (0.44) MAPK1SMN1; SMN2CA2PARP1
SCHEMBL359496 0.80 CA2 (0.42) MAPK1SMN1; SMN2CA2PARP1LCK
SCHEMBL30519265 0.78 DDR1 (0.46) ALDH1A1KDM4EHSD17B10
SCHEMBL365842 0.77 TSHR (0.47) SMN1; SMN2CA2KMT2AALDH1A1KDM4E
SCHEMBL17278828 0.76 HSP90AA1 (0.38) SMN1; SMN2KMT2AALDH1A1
SCHEMBL5006032 0.74 MAPK1 (0.45) MAPK1PARP10SMN1; SMN2CA2PARP1
SCHEMBL28670313 0.73 GAA (0.47) MAPK1SMN1; SMN2CA2PARP1ALDH1A1
SCHEMBL28349856 0.73 PSIP1 (0.44) CA2
SCHEMBL2911414 0.72 SLC9A1 (0.42) SMN1; SMN2CA2ALDH1A1
SCHEMBL17689138 0.72 SLC9A1 (0.42) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1128730-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE Novozymes A/S (DK) 2001-09-05 EP disclosed
WO-2000027204-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2000-05-18 WO disclosed