Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15675992 | 0.83 | ESR1 (0.48) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL3909491 | 0.82 | ALOX15 (0.52) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL3434639 | 0.81 | ESR1 (0.44) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL375159 | 0.79 | ESR1 (0.42) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL29872696 | 0.75 | ALOX15 (0.52) | ESR1ESR2ALOX15CYP2D6CYP2C9 | |
| SCHEMBL1245497 | 0.75 | ALOX15 (0.52) | ESR1ESR2ALOX15CYP2D6CYP2C9 | |
| SCHEMBL2287328 | 0.75 | ALDH1A1 (0.50) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL17864634 | 0.73 | ALDH1A1 (0.48) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL8861305 | 0.72 | ALOX15 (0.44) | ESR1ESR2ARALOX15CYP2D6 | |
| SCHEMBL70123 | 0.72 | MAPT (0.75) | ESR1ESR2ARALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496640-B2 | I-ray sensitive positive resist composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 2001-09-19 | — | — | EP | claimed |