Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861330 | 0.83 | ESR1 (0.45) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL29498346 | 0.83 | ALOX15 (0.53) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL225503 | 0.83 | ALOX15 (0.53) | ESR1ESR2ARCYP2D6CYP2C9 | |
| Butylated Hydroxytoluene SCHEMBL8487462 | 0.76 | ALDH1A1 (0.53) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL28255701 | 0.75 | KDM4E (0.40) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL8861301 | 0.74 | ESR1 (0.47) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL9853953 | 0.74 | CNR1 (0.39) | ESR1ESR2AR | |
| SCHEMBL3434639 | 0.73 | ESR1 (0.44) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL375159 | 0.72 | ESR1 (0.42) | ESR1ESR2ARCYP2D6CYP2C9 | |
| SCHEMBL29872696 | 0.72 | ALOX15 (0.52) | ESR1ESR2CYP2D6CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9256126-B2 | Methanofullerenes | IRRESISTIBLE MATERIALS LTD (GB) | 2016-02-09 | — | — | US | disclosed |
| US-20140134843-A1 | Methanofullerenes | IRRESISTIBLE MATERIALS LTD (GB) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140134843-A1 | Methanofullerenes | WASF2, ERCC4, TUFM | ESR1 1036/4885ESR2 1065/4885AR 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.