Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 5/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289576 | 0.79 | PSMB8 (0.41) | PSMB8NOS1DAODYRK1ARHEB | |
| SCHEMBL7800470 | 0.68 | PSMB8 (0.39) | PSMB8NOS1FEN1CYP2A6 | |
| SCHEMBL20276479 | 0.64 | ERCC5 (0.50) | PSMB8NOS1DYRK1AERCC5FEN1 | |
| SCHEMBL21145351 | 0.63 | GABRP (0.48) | DAODYRK1AERCC5FEN1 | |
| SCHEMBL6009055 | 0.63 | ERCC5 (0.53) | PSMB8NOS1DYRK1AERCC5FEN1 | |
| SCHEMBL31619545 | 0.63 | ERCC5 (0.53) | PSMB8NOS1DYRK1AERCC5FEN1 | |
| SCHEMBL321694 | 0.63 | GPR84 (0.41) | PSMB8NOS1DAODYRK1ARHEB | |
| SCHEMBL558395 | 0.61 | NOS1 (0.42) | PSMB8NOS1GPR84GAACYP1A2 | |
| SCHEMBL7459887 | 0.60 | GPR84 (0.39) | PSMB8NOS1DYRK1AERCC5FEN1 | |
| SCHEMBL31534795 | 0.60 | PSMB8 (0.56) | PSMB8NOS1GAAADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773765-A1 | METHODS USING ACYL-COENZYME A-BINDING PROTEINS TO ENHANCE DROUGHT TOLERANCE IN GENETICALLY MODIFIED PLANTS | The University of Hong Kong (CN) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064119-A1 | METHODS USING ACYL-COENZYME A-BINDING PROTEINS TO ENHANCE DROUGHT TOLERANCE IN GENETICALLY MODIFIED PLANTS | THE UNIVERSITY OF HONG KONG (CN) | 2013-05-10 | — | — | WO | disclosed |
| US-20010055590-A1 | Method for enhancing myoblast migration and invasion in the context of gene therapy | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2001-12-27 | — | — | US | disclosed |