Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559800 | 0.80 | NQO2 (0.70) | NQO2CYP19A1KDM4EHSD17B10ATM | |
| SCHEMBL14931060 | 0.77 | HSD17B10 (0.46) | HSD17B10BRD4HPGDALDH1A1 | |
| SCHEMBL24105882 | 0.77 | ALKBH5 (0.58) | KDM4EHSD17B10KCNA3ATMBRD4 | |
| SCHEMBL11503490 | 0.76 | NQO2 (0.64) | NQO2CYP19A1KDM4EHSD17B10ATM | |
| SCHEMBL21023175 | 0.75 | HSD17B10 (0.50) | KDM4EHSD17B10ATMBRD4HPGD | |
| SCHEMBL17509827 | 0.74 | NQO2 (1.00) | NQO2CYP19A1KDM4EHSD17B10ATM | |
| SCHEMBL24105867 | 0.74 | ALKBH5 (0.54) | KDM4EHSD17B10KCNA3BRD4MAPT | |
| SCHEMBL21156638 | 0.73 | HSD17B10 (0.44) | KDM4EHSD17B10ATMBRD4HPGD | |
| SCHEMBL17030415 | 0.71 | ALKBH5 (0.59) | KDM4EHSD17B10BRD4HPGDALDH1A1 | |
| SCHEMBL26242847 | 0.71 | HSD17B10 (0.41) | KDM4EHSD17B10BRD4HPGDRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675924-B1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES INC (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0675924-A1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES, INC. (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5436134-A | Fluorescent dyes for nucleic acids | MOLECULAR PROBES, INC. (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1994024213-A1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES, INC. (US) | 1994-10-27 | — | — | WO | disclosed |