SCHEMBL7861398

SCHEMBL7861398

C[C](C)CCCCCCN(C)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.67
KDM4A O75164 2/20 0.61
KDM4C Q9H3R0 2/20 0.61
HTR7 P34969 4/20 0.58
MAOB P27338 2/20 0.55
MAOA P21397 1/20 0.55
APP P05067 2/20 0.53
CARM1 Q86X55 1/20 0.53
PRMT6 Q96LA8 1/20 0.53
PRMT8 Q9NR22 1/20 0.53
ACHE P22303 6/20 0.52
BCHE P06276 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
TMEM97 Q5BJF2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733117 0.87 SIGMAR1 (0.85) SIGMAR1KDM4AKDM4CMAOBMAOA
SCHEMBL7225346 0.87 SIGMAR1 (0.85) SIGMAR1KDM4AKDM4CMAOBMAOA
SCHEMBL7205122 0.85 KDM4A (0.76) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL7855918 0.83 SIGMAR1 (0.51) SIGMAR1KDM4AKDM4CHTR7ACHE
SCHEMBL7398852 0.83 KDM4A (0.74) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL10925712 0.82 SIGMAR1 (0.71) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL10655267 0.82 SIGMAR1 (0.71) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL21851808 0.82 SIGMAR1 (0.71) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL7435010 0.82 SIGMAR1 (0.71) SIGMAR1KDM4AKDM4CHTR7MAOB
SCHEMBL4016132 0.82 SIGMAR1 (0.71) SIGMAR1KDM4AKDM4CHTR7MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623608-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LTD (JP) 2001-05-30 EP disclosed
EP-0632031-B1 CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LTD (JP) 2000-05-03 EP disclosed
EP-0546177-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LTD (JP) 1998-01-07 EP disclosed
US-5574061-A ANTILIPEMIC AGENT, ANTIATHEROSCLEROSIS, ACAT INHIBITOR TEIJIN LIMITED (JP) 1996-11-12 US disclosed
US-5496853-A FOR TREATING HYPERCHOLESTEROLEMIA TEIJIN LIMITED (JP) 1996-03-05 US disclosed
EP-0632031-A1 CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 1995-01-04 EP disclosed
EP-0623608-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1994-11-09 EP disclosed
EP-0546177-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 1993-06-16 EP disclosed