SCHEMBL7861440

SCHEMBL7861440

CC1=Cc2cc(-c3cccc4ccccc34)ccc2C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
TLR8 Q9NR97 1/20 0.38
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
SLC6A2 P23975 1/20 0.38
CHRNB4 P30926 1/20 0.38
SLC6A4 P31645 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CHRND Q07001 1/20 0.38
CA12 O43570 5/20 0.38
CA9 Q16790 5/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2962487 0.77 CNR1 (0.36) MCL1ACMSDENPP3ENPP1CHRNA1
SCHEMBL4895432 0.77 MCL1 (0.47) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL29785059 0.77 MCL1 (0.47) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL3137217 0.77 MCL1 (0.47) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL29732348 0.77 MCL1 (0.47) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL2970618 0.77 CA12 (0.36) ENPP3ENPP1CA12CA9CA1
SCHEMBL2972909 0.77 CA12 (0.36) ENPP3ENPP1CA12CA9CA1
Ammonia Solution, Strong SCHEMBL29226614 0.76 MCL1 (0.46) MCL1ACMSDENPP3ENPP1CA12
SCHEMBL31589402 0.75 TDP2 (0.41) ALDH1A1
SCHEMBL4431843 0.74 MCL1 (0.45) MCL1ACMSDENPP3ENPP1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141034-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP Chemicals Limited (GB) 2001-10-10 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed