SCHEMBL2962487

SCHEMBL2962487

CC1=Cc2cc(-c3cccc4ccccc34)cc(Br)c2C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
SLC6A2 P23975 1/20 0.36
CHRNB4 P30926 1/20 0.36
SLC6A4 P31645 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CHRND Q07001 1/20 0.36
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35
CA12 O43570 6/20 0.35
CA9 Q16790 6/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
HDAC8 Q9BY41 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959376 0.83 GRIA1 (0.35) CA12CA9CA1CA2MCL1
SCHEMBL2959123 0.81 S1PR1 (0.30) S1PR1
SCHEMBL2969412 0.80 CNR1 (0.37) CNR1CNR2CHRNA1CHRNGCHRNB1
SCHEMBL2970981 0.80 KDM4E (0.34) CNR1CNR2ENPP3ENPP1CA12
SCHEMBL2972163 0.78 CRHBP (0.43) KDM4EALDH1A1BRD4
SCHEMBL7861440 0.77 MCL1 (0.41) CNR1CNR2CHRNA1CHRNGCHRNB1
SCHEMBL2963346 0.77 DHFR (0.38) SLC6A3ENPP3ENPP1CA12CA9
SCHEMBL29776182 0.75 HTR7 (0.40) SLC6A3ENPP3ENPP1CA12CA9
SCHEMBL3155099 0.75 HTR7 (0.40) SLC6A3ENPP3ENPP1CA12CA9
SCHEMBL2970307 0.75 HTR7 (0.34) SLC6A3ENPP3ENPP1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 CNR1 3262/4885CNR2 3221/4885CHRNA1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.