Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 4/20 | 0.53 |
| ▸ | PGR | P06401 | 4/20 | 0.53 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862455 | 0.91 | SHBG (0.56) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7861224 | 0.89 | PGR (0.53) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7862281 | 0.85 | CYP3A4 (0.58) | SHBGPGRARESR1CYP3A4 | |
| SCHEMBL7860061 | 0.83 | PGR (0.51) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7862295 | 0.83 | PGR (0.51) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7854406 | 0.83 | PGR (0.51) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7861412 | 0.82 | PGR (0.50) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7862380 | 0.82 | PGR (0.50) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7861396 | 0.82 | PGR (0.50) | SHBGPGRARESR1OPRM1 | |
| SCHEMBL7859919 | 0.82 | PGR (0.50) | SHBGPGRARESR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709394-B1 | Steroids with a 17-spiromethylene lactone or lactol group | AKZO NOBEL NV (NL) | 2001-01-31 | — | — | EP | disclosed |
| US-5741786-A | PROGESTATIONAL ACTIVITY, USED AS CONTRACEPTIVES | AKZO NOBEL N.V. (NL) | 1998-04-21 | — | — | US | disclosed |
| EP-0709394-A2 | Steroids with a 17-spiromethylene lactone or lactol group | Akzo Nobel N.V. (NL) | 1996-05-01 | — | — | EP | disclosed |