Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | PGR | P06401 | 4/20 | 0.58 |
| ▸ | SHBG | P04278 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859958 | 0.88 | CYP3A4 (0.58) | CYP3A4ABCB11LMNAPGRSHBG | |
| SCHEMBL8427160 | 0.87 | PGR (0.61) | CYP3A4ABCB11LMNAPGRSHBG | |
| SCHEMBL7861454 | 0.85 | SHBG (0.53) | CYP3A4ABCB11LMNAPGRSHBG | |
| SCHEMBL11596660 | 0.83 | CYP3A4 (0.64) | CYP3A4ABCB11LMNAPGRSHBG | |
| SCHEMBL11475742 | 0.83 | CYP3A4 (0.64) | CYP3A4ABCB11LMNAPGRSHBG | |
| SCHEMBL11645201 | 0.82 | CYP3A4 (0.66) | CYP3A4ABCB11LMNAPGRSHBG | |
| Gestonorone SCHEMBL141624 | 0.81 | CYP3A4 (0.67) | CYP3A4ABCB11LMNAPGRSHBG | |
| Gestonorone SCHEMBL17831152 | 0.81 | CYP3A4 (0.67) | CYP3A4ABCB11LMNAPGRSHBG | |
| Gestonorone SCHEMBL20488186 | 0.81 | CYP3A4 (0.67) | CYP3A4ABCB11LMNAPGRSHBG | |
| Gestonorone SCHEMBL17831151 | 0.81 | CYP3A4 (0.67) | CYP3A4ABCB11LMNAPGRSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709394-B1 | Steroids with a 17-spiromethylene lactone or lactol group | AKZO NOBEL NV (NL) | 2001-01-31 | — | — | EP | disclosed |
| US-5741786-A | PROGESTATIONAL ACTIVITY, USED AS CONTRACEPTIVES | AKZO NOBEL N.V. (NL) | 1998-04-21 | — | — | US | disclosed |
| EP-0709394-A2 | Steroids with a 17-spiromethylene lactone or lactol group | Akzo Nobel N.V. (NL) | 1996-05-01 | — | — | EP | disclosed |