Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418958 | 0.85 | THRB (0.37) | ALDH1A1THRB | |
| SCHEMBL51240 | 0.81 | THRB (0.45) | ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL31483665 | 0.79 | THRB (0.41) | ALDH1A1THRB | |
| Methyl Alcohol SCHEMBL9341506 | 0.78 | THRB (0.43) | ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL51996 | 0.76 | — | — | |
| Methyl Alcohol SCHEMBL8767279 | 0.76 | THRB (0.39) | ALDH1A1THRB | |
| SCHEMBL15124468 | 0.75 | ALDH1A1 (0.50) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL51195 | 0.75 | — | — | |
| SCHEMBL2833636 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL14218206 | 0.74 | LMNA (0.34) | ALDH1A1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740679-B1 | CROSSLINKED POLYMERIC AMMONIUM SALTS | DU PONT (US) | 2001-08-08 | — | — | EP | claimed |
| US-5874522-A | FORMING CROSSLINKED POLYMERIC AMMONIUM SALT OR POLYMERIC AMINE IN SOLVENT, WHEREIN TEMPLATE COMPRISING SACCHARIDE OR ORGANIC METAL SALT IS PRESENT WHEN THE CROSSLINKED POLYMERIC AMMONIUM SALT OR POLYMERIC AMINE GELS; BILE ACID SEQUESTRANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-02-23 | — | — | US | claimed |
| US-5726284-A | Crosslinked polymric ammonium salts | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-10 | — | — | US | claimed |
| US-5556619-A | BILE ACID SEQUESTERANTS TO LOWER BLOOD CHOLESTEROL, POLYAMINES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-17 | — | — | US | claimed |