Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 6/20 | 0.37 |
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476639 | 1.00 | CYP2D6 (0.45) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL7853722 | 0.82 | CA2 (0.45) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL7859375 | 0.82 | CA2 (0.45) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL8849673 | 0.81 | CYP2D6 (0.40) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL8582142 | 0.81 | CYP2D6 (0.40) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL8480885 | 0.81 | CYP2D6 (0.52) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL7859120 | 0.81 | CYP2D6 (0.52) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL27670281 | 0.74 | PPARA (0.48) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL7861519 | 0.74 | CA1 (0.58) | CYP2D6CA1CA2CA7CTSK | |
| SCHEMBL7861496 | 0.74 | PPARG (0.37) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |