Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853722 | 1.00 | CA2 (0.45) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL7861519 | 0.84 | CA1 (0.58) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL7861485 | 0.82 | CYP2D6 (0.45) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL8476639 | 0.82 | CYP2D6 (0.45) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL7863783 | 0.82 | AAK1 (0.48) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL7861529 | 0.81 | CTSK (0.40) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL27670281 | 0.81 | PPARA (0.48) | CA2CA1CA7CTSKCTSS | |
| SCHEMBL7861496 | 0.81 | PPARG (0.37) | CA2CA1CA7CTSKCTSS | |
| SCHEMBL19084258 | 0.79 | CA1 (0.53) | CA2CA1CA7CYP2D6CTSK | |
| SCHEMBL7853765 | 0.79 | CTSK (0.43) | CA2CA1CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5925658-A | PREVENTING OR TREATING ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5891898-A | ANTIULCER AGENT | SANKYO COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |