Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 10/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853722 | 0.84 | CA2 (0.45) | CA1CA2CA7CA4CA9 | |
| SCHEMBL7859375 | 0.84 | CA2 (0.45) | CA1CA2CA7CA4CA9 | |
| SCHEMBL7861529 | 0.82 | CTSK (0.40) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL7863783 | 0.79 | AAK1 (0.48) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL12396265 | 0.79 | CA1 (0.67) | CA1CA2CA7CA4CA9 | |
| SCHEMBL3370592 | 0.79 | CA1 (0.67) | CA1CA2CA7CA4CA9 | |
| SCHEMBL7420759 | 0.79 | CA1 (0.67) | CA1CA2CA7CA4CA9 | |
| SCHEMBL27670281 | 0.79 | PPARA (0.48) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL38665117 | 0.79 | CA1 (0.71) | CA1CA2CA7CA4CA9 | |
| SCHEMBL14098271 | 0.79 | CA1 (0.71) | CA1CA2CA7CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5925658-A | PREVENTING OR TREATING ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5891898-A | ANTIULCER AGENT | SANKYO COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |