Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861658 | 1.00 | HRH1 (0.48) | HRH1KDM4EKCNH2MEN1TSHR | |
| SCHEMBL7854950 | 0.82 | KDM4E (0.45) | HRH1KDM4EKCNH2MEN1TSHR | |
| SCHEMBL7854951 | 0.82 | KDM4E (0.45) | HRH1KDM4EKCNH2MEN1TSHR | |
| Oxalic Acid SCHEMBL7864914 | 0.79 | HRH1 (0.45) | HRH1KDM4EKCNH2 | |
| Oxalic Acid SCHEMBL7864912 | 0.79 | HRH1 (0.45) | HRH1KDM4EKCNH2 | |
| SCHEMBL7865024 | 0.75 | HRH1 (0.44) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL7865017 | 0.75 | HRH1 (0.44) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL7861738 | 0.72 | KCNH2 (0.43) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL7861741 | 0.72 | KCNH2 (0.43) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL9535375 | 0.71 | HRH1 (0.55) | HRH1KDM4EKCNH2TSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869955-B1 | N-ACYL-2-SUBSTITUTED-4-(BENZIMIDAZOLYL- OR IMIDAZOPYRIDINYL-SUBSTITUTED RESIDUES)-PIPERIDINES AS TACHYKININ ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-24 | — | — | EP | disclosed |