Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31197981 | 0.80 | MMP9 (0.51) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL7860490 | 0.77 | ATM (0.45) | MAPTALDH1A1ATMTSHR | |
| SCHEMBL3344785 | 0.77 | CA1 (0.47) | MAPTALDH1A1LMNAKDM4EDAO | |
| SCHEMBL3733635 | 0.76 | LMNA (0.60) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL16689961 | 0.73 | KMT2A (0.67) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL3344960 | 0.73 | PTPN5 (0.47) | NPC1RAB9ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL5334332 | 0.71 | MMP9 (0.59) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL1129093 | 0.70 | MEN1 (0.77) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL2842512 | 0.70 | KMT2A (0.71) | MMP9MMP1NPC1MAPTRAB9A | |
| SCHEMBL3729736 | 0.70 | MAPT (0.58) | MMP9MMP1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |