Oxazole

Oxazole

SCHEMBL7862230

c1ccc2c(c1)ccc1ncsc12.c1cocn1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
LMNA P02545 3/20 0.33
MAPT P10636 3/20 0.33
PLAU P00749 2/20 0.33
APEX1 P27695 1/20 0.33
MAPK1 P28482 1/20 0.33
PMP22 Q01453 1/20 0.33
CYP2A6 P11509 1/20 0.33
F12 P00748 1/20 0.33
NCF1 P14598 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
BACE1 P56817 1/20 0.33
NPC1 O15118 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PLG P00747 1/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29871387 0.83 CYP3A4 (0.47) CYP3A4LMNAMAPTPLAUAPEX1
SCHEMBL2852558 0.83 CYP3A4 (0.47) CYP3A4LMNAMAPTPLAUAPEX1
Phenanthrene SCHEMBL27708213 0.78 ALDH1A1 (0.50) CYP3A4LMNAMAPTPLAUAPEX1
SCHEMBL4154752 0.76 HPRT1 (0.50) CYP3A4LMNAMAPTAPEX1MAPK1
SCHEMBL28846419 0.76 HPRT1 (0.50) CYP3A4LMNAMAPTAPEX1MAPK1
Benzo[D]Thiazole SCHEMBL1133662 0.73 ALDH1A1 (0.63) NPC1RAB9ASMN1; SMN2HSD17B10ALDH1A1
SCHEMBL11565679 0.72 ALDH1A1 (0.41) CYP3A4LMNAMAPTCYP2A6NPC1
SCHEMBL25647644 0.72 CYP3A4 (0.43) CYP3A4LMNAMAPTMAPK1CYP2A6
Triphenylene SCHEMBL21381928 0.71 LMNA (0.32) CYP3A4LMNAMAPTPLAUAPEX1
Naphthalene SCHEMBL303948 0.71 CYP2A6 (0.40) PLAUCYP2A6F12NCF1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197968-B1 STORAGE STABILITY; COLORLESS AFTER SOLUTION TREATMENT FUJI PHOTO FILM CO., LTD. (JP) 2001-03-06 US claimed