Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | NCF1 | P14598 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL9615518 | 1.00 | CYP2A6 (0.40) | CYP2A6ALOX12CYP11B1CYP11B2CYP19A1 | |
| Anthracene SCHEMBL26926677 | 0.91 | ALDH1A1 (0.37) | CYP2A6ALOX12CYP11B1CYP11B2CYP19A1 | |
| Oxazole SCHEMBL29213663 | 0.89 | — | — | |
| Isoquinoline SCHEMBL27772897 | 0.88 | TNF (0.37) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| Phenanthrene SCHEMBL27708213 | 0.87 | ALDH1A1 (0.50) | CYP2A6PLAUNCF1NOS2BACE1 | |
| Triphenylene SCHEMBL21381928 | 0.85 | LMNA (0.32) | CYP2A6CYP11B1PLAUNCF1NOS2 | |
| Pyrene SCHEMBL3808718 | 0.84 | ALDH1A1 (0.48) | ALDH1A1 | |
| Oxazole SCHEMBL9215176 | 0.83 | CYP2A6 (0.59) | CYP2A6CYP11B1CYP11B2CYP19A1CYP17A1 | |
| Biphenyl SCHEMBL29228469 | 0.83 | NOTUM (0.50) | CYP2A6CYP19A1PLAUALDH1A1 | |
| Biphenyl SCHEMBL944174 | 0.83 | NOTUM (0.50) | CYP2A6CYP19A1PLAUALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702546-B2 | Near-infrared heptamethine dyes for generation of singlet oxygen | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-07-18 | — | — | US | claimed |
| US-20230173071-A1 | TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT | CALIFORNIA INST OF TECHN (US) | 2023-06-08 | — | — | US | claimed |
| US-20200129620-A1 | Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-04-30 | — | — | US | claimed |
| US-20200131370-A1 | Near-Infrared Heptamethine Dyes For Generation Of Singlet Oxygen | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-04-30 | — | — | US | claimed |
| CN-106715420-A | crosslinkable host material | 西诺拉股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-101460223-A | Quinolones as Inducible Nitric Oxide Synthase Inhibitors | KALYPSYS INC (US) | 2009-06-17 | — | — | CN | claimed |
| EP-1609459-B1 | Use of polycationic compounds for dyeing keratinous fibers | OREAL (FR) | 2009-04-08 | — | — | EP | claimed |
| JP-2008510698-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1774047-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | University of Utah Research Foundation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006121423-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2006-11-16 | — | — | WO | claimed |
| US-5410030-A | Nucleic acid stains | MOLECULAR PROBES, INC. (US) | 1995-04-25 | — | — | US | claimed |
| EP-0568267-A2 | Thermal transfer materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-03 | — | — | EP | claimed |
| US-5216166-A | Cyanine dye with nitro group substituent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-01 | — | — | US | claimed |
| EP-0465078-A1 | Infra-red sensitive photographic materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-08 | — | — | EP | claimed |
| US-5030553-A | Low minimum image density, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-09 | — | — | US | claimed |
| EP-0399460-A2 | Silver halide photograpic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-28 | — | — | EP | claimed |
| EP-0303301-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-15 | — | — | EP | claimed |
| US-4463087-A | Controlled site epitaxial sensitization of limited iodide silver halide emulsions | EASTMAN KODAK COMPANY (US) | 1984-07-31 | — | — | US | claimed |
| US-4435501-A | SILVER HALIDE EMULSIONS | EASTMAN KODAK COMPANY (US) | 1984-03-06 | — | — | US | claimed |
| US-4425426-A | SENSITIZING DYE ADSORBED TO SILVER HALIDE GRAINS | EASTMAN KODAK COMPANY (US) | 1984-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129620-A1 | Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light | CRY1, MYH10, MYLK | CYP2A6 2287/4885ALOX12 258/4885CYP11B1 982/4885 |
| US-20230173071-A1 | TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT | CRY1, MYH10, MYLK | CYP2A6 2287/4885ALOX12 258/4885CYP11B1 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.