Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862275 | 0.84 | NPC1 (0.57) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL7775228 | 0.79 | NPC1 (0.57) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL8570774 | 0.77 | BLM (0.44) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL29023341 | 0.76 | RXRA (0.48) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| Cyanide SCHEMBL30294043 | 0.74 | RXRA (0.46) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL29023340 | 0.73 | FFAR1 (0.46) | NPC1MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL7776919 | 0.73 | PARP10 (0.57) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL5729777 | 0.73 | PARP10 (0.53) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL8026374 | 0.72 | NPC1 (0.52) | NPC1MAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL7619158 | 0.72 | NPC1 (0.52) | NPC1MAPTRAB9APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300454-B1 | Liquid-crystalline nematic organosiloxanes which can be crosslinked to form optically anisotropic polymer layers | WACKER-CHEMIE GMBH (DE) | 2001-10-09 | — | — | US | disclosed |