Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775228 | 0.90 | NPC1 (0.57) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7862273 | 0.84 | NPC1 (0.51) | NPC1MAPTRAB9AHRH3ADRB2 | |
| SCHEMBL7619158 | 0.84 | NPC1 (0.52) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL8026374 | 0.84 | NPC1 (0.52) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7626930 | 0.78 | ADRB2 (0.48) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL8861912 | 0.78 | ALDH1A1 (0.56) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7776919 | 0.78 | PARP10 (0.57) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL9446934 | 0.78 | ADRB2 (0.48) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL5729777 | 0.78 | PARP10 (0.53) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL2831629 | 0.78 | MAPT (0.49) | NPC1MAPTRAB9AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300454-B1 | Liquid-crystalline nematic organosiloxanes which can be crosslinked to form optically anisotropic polymer layers | WACKER-CHEMIE GMBH (DE) | 2001-10-09 | — | — | US | disclosed |