Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627772 | 0.91 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7869010 | 0.89 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL6629826 | 0.81 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL6624997 | 0.79 | FNTA (0.52) | FNTAFNTBBRS3 | |
| SCHEMBL7916485 | 0.78 | FNTA (0.45) | FNTAFNTBBRS3 | |
| SCHEMBL628888 | 0.78 | FNTA (0.51) | FNTAFNTBBRS3 | |
| SCHEMBL629682 | 0.75 | FNTA (0.69) | FNTAFNTB | |
| SCHEMBL629681 | 0.75 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL6627774 | 0.74 | FNTA (0.44) | FNTAFNTBBRS3 | |
| SCHEMBL7915252 | 0.74 | FNTA (0.46) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |