SCHEMBL7869010

SCHEMBL7869010

COC(=O)c1ccc(C[N+](C)(C)CCC2CCCCC2)cc1-c1ccccc1C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7862461 0.89 FNTA (0.43) FNTAFNTB
SCHEMBL6627772 0.88 FNTA (0.42) FNTAFNTB
Decarboxylated Derivative SCHEMBL628807 0.80 FNTA (0.41) FNTAFNTB
SCHEMBL630166 0.79 FNTA (0.49) FNTAFNTB
Decarboxylated Derivative SCHEMBL629210 0.79 FNTA (0.41) FNTAFNTB
SCHEMBL628806 0.79 MEN1 (0.41)
SCHEMBL6629826 0.79 FNTA (0.68) FNTAFNTB
Hydrochloric Acid SCHEMBL629209 0.78 MEN1 (0.41)
SCHEMBL7869097 0.78 NPC1 (0.56)
SCHEMBL7917853 0.77 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed