Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869174 | 0.93 | MMP3 (0.45) | FNTAFNTBMMP3CNR2STAT3 | |
| SCHEMBL7862401 | 0.91 | FNTA (0.46) | FNTAFNTBCNR2STAT3NPSR1 | |
| SCHEMBL7862519 | 0.89 | MMP3 (0.54) | FNTAFNTBMMP3TAS2R14PTGES | |
| SCHEMBL7862520 | 0.89 | MMP3 (0.46) | FNTAFNTBMMP3STAT3TAS2R14 | |
| SCHEMBL7862459 | 0.89 | FNTA (0.48) | FNTAFNTBMMP3STAT3TAS2R14 | |
| SCHEMBL7869003 | 0.87 | MAPK1 (0.44) | FNTAFNTBMMP3STAT3 | |
| SCHEMBL628907 | 0.85 | FNTA (0.49) | FNTAFNTBMMP3 | |
| SCHEMBL7867324 | 0.84 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL7874245 | 0.83 | STAT3 (0.48) | FNTAFNTBCNR2STAT3TAS2R14 | |
| SCHEMBL10192973 | 0.83 | FNTA (0.47) | FNTAFNTBMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |