Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862519 | 0.94 | MMP3 (0.54) | MMP3FNTAFNTBTAS2R14PTGES | |
| SCHEMBL7862520 | 0.94 | MMP3 (0.46) | MMP3FNTAFNTBSTAT3TAS2R14 | |
| SCHEMBL7862462 | 0.93 | FNTA (0.44) | MMP3FNTAFNTBSTAT3CNR2 | |
| SCHEMBL7862459 | 0.92 | FNTA (0.48) | MMP3FNTAFNTBSTAT3TAS2R14 | |
| SCHEMBL7869003 | 0.91 | MAPK1 (0.44) | MMP3FNTAFNTBSTAT3MAPT | |
| SCHEMBL7874245 | 0.91 | STAT3 (0.48) | FNTAFNTBSTAT3CNR1CNR2 | |
| SCHEMBL628907 | 0.86 | FNTA (0.49) | MMP3FNTAFNTB | |
| SCHEMBL7871302 | 0.84 | FNTA (0.46) | MMP3FNTAFNTBSTAT3TAS2R14 | |
| SCHEMBL10192973 | 0.84 | FNTA (0.47) | MMP3FNTAFNTB | |
| SCHEMBL6626900 | 0.83 | FNTA (0.62) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |